Description

This logic path evaluates criteria for when to stop screening for colorectal cancer, and determines whether the patient is eligible for average risk screening, based on the risk factors outlined by USPSTF.

Mid-Level Flow Diagram

Age >= 86 years old?Age >= 76 years old?Recommendation: Selectively offerscreeningLife expectancy <10years?Recommendation: Discuss decisionto continue screeningHas risk factor(s) forcolorectal cancer?Recommendation: Stop screeningAverage risk screeningIncreased riskscreening/surveillancenoyesnoyesyesnonoyes

Semi-Structured Logic Statements

Inclusions

NameDescription
Patients eligible for screening
Patients for whom screening is clinically appropriate.
See 'Screening Eligible' logic path

Exclusions

None.

Events

NameDescription
Life expectancy <10 years?
Life expectancy, generally defined as having greater than a 50% probability of surviving 10 years, is < 10 years. A validated tool such as www.eprognosis.com can help guide decision making.
Age >= 76 years old?
Age >= 76 years old
Age >= 86 years old?
Age >= 86 years old
Has risk factor(s) for colorectal cancer?
See 'Increased Risk Exclusions' logic path

Actions

Average risk screening
Description
Patients who do not meet criteria for increased risk of colorectal cancer (as defined by USPSTF) can be screened as average risk patinnts.
Pseudocode
See 'Average Risk Screening' logic path.
Recommendation: Stop screening
Description
Recommendation: Evidence is lacking on benefits and harms of colorectal cancer screening for individuals aged 86 and older. Competing causes of mortality likely preclude survival benefit that would outweigh the harms of screening.
Pseudocode
Recommendation: Selectively offer screening
Description
The USPSTF recommends that clinicians selectively offer screening for colorectal cancer in adults aged 76 to 85 years.

Source: USPSTF, 2021
Pseudocode
Recommendation: Discuss decision to continue screening
Description
ACS advises that individuals should continue colorectal cancer screening as long as their overall health is good and they have a life expectancy of 10 years or more. Decision to continue screening in cases of limited life expectancy should be based on shared decision-making.

Source: ACS (2018)
Pseudocode
Increased risk screening/surveillance
Description
Patient is at increased risk for colorectal cancer based on one or more non-modifiable risk factors.
Pseudocode
See 'Increased Risk Exclusions' logic path for specific increased risk populations and recommendations for increased risk screening/surveillance.

References

  • ACS (2018): Wolf, A. M. D., et al. (2018). Colorectal cancer screening for average‐risk adults: 2018 guideline update from the American Cancer Society. CA: A Cancer Journal for Clinicians, 68(4), 250–281. https://doi.org/10.3322/caac.21457
  • USMSTF (2017): Rex, D. K., et al. (2017). Colorectal Cancer Screening: Recommendations for Physicians and Patients From the U.S. Multi-Society Task Force on Colorectal Cancer. Gastroenterology, 153(1), 307-323. https://doi.org/10.1053/j.gastro.2017.05.013
  • USPSTF (2021): Davidson, K. W., et al. (2021). Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement. JAMA - Journal of the American Medical Association, 325(19), 1965-1977. https://doi.org/10.1001/jama.2021.6238

Approved for Public Release, Distribution Unlimited.
Public Release Case Number 24-2711
Copyright ©2024 The MITRE Corporation. All rights reserved.